Join us !

This proget is carried out in collaboration with the group of Prof Michele Maggini. It focuses on the synthesis of fullerene‑based nitroxides as molecular probes and on the investigation of light‑driven NMR hyperpolarization mechanisms, with the goal of boosting signal sensitivity far beyond thermal equilibrium.

It is an excellent opportunity for a motivated student interested in combining organic chemistry and magnetic resonance spectroscopy. The work has strong potential to lead to a scientific publication.

Skills acquisition:

• Synthesis and purification of functionalized [60]fullerenes

• Structural characterization (NMR, MS, IR)

• Hands‑on NMR hyperpolarization: sample preparation, optimization, and data interpretation

This project explores an innovative strategy to overcome the intrinsic sensitivity limits of NMR by using light to amplify nuclear spin signals in solution. We will investigate chromophore–radical molecular systems in which optical excitation generates electron spin polarization that can be transferred to nuclei, enhancing the NMR signal at room temperature and without the need for microwaves. 

What will you do?

• Test different chromophore–radical pairs (e.g., porphyrins, fullerenes, organic dyes)

• Optimize solvents and concentrations

• Measure NMR signal enhancement under light irradiation

• Investigate spin‑transfer mechanisms using NMR and EPR

Why this project?

• It is a highly interdisciplinary topic at the interface of chemistry, physics, and spectroscopy, with strong potential for innovative results and scientific publications.

Who are we looking for?

• Ideal for motivated students interested in experimental research and advanced magnetic resonance techniques, who want to work at the frontier between molecular design and spin physics.

Skills acquisition:

• Structural characterization (NMR, EPR)

• Hands‑on NMR hyperpolarization: sample preparation, optimization, and data interpretation